T-cell receptors: Feeling out the complex

نویسندگان

  • Eduardo A. Padlan
  • David H. Margulies
چکیده

Recent crystallographic studies show that the T-cell receptor has a largely immunoglobulin-like structure and binds to MHC-peptide complexes through loops from paired Valpha and Vbeta domains that focus on the central amino acids of the MHC-bound peptide, and to bacterial superantigens via peripheral aspects of the Vbeta domain.

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عنوان ژورنال:
  • Current Biology

دوره 7  شماره 

صفحات  -

تاریخ انتشار 1997